CYP2E1 Rsa I polymorphism impacts on risk of colorectal cancer association with smoking and alcohol drinking

doi:10.3748/wjg.v13.i43.5725

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Nov 21, 2007 (publication date) through Feb 21, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 21, 2007; 13(43): 5725-5730
Published online Nov 21, 2007. doi: 10.3748/wjg.v13.i43.5725

Table 3 Logistic regression analysis on smoking, alcohol drinking and CYP2E1 c2/c2 genotypes and risk of colorectal cancer

	Colorectal cancer OR¹ (95% CI)	Colon cancer OR¹ (95% CI)	Rectal cancer OR¹ (95% CI)
Smoking	1.01 (0.69-1.47)	0.84 (0.49-1.44)	1.08 (0.70-1.67)
Alcohol drinking	1.91 (1.31-2.80)	1.68 (0.97-2.89)	2.08 (1.36-3.19)
CYP2E1 c2/c2	1.50 (1.05-2.15)	1.34 (0.81-2.23)	1.58 (1.08-2.32)

¹Logistic regression model included age (continuous), sex, smoking (nonsmoker, current + former smoker), alcohol drinking (nondrinker, current + former drinker) and CYP2E1 genotype (c1/c1 + c1/c2, c2/c2).

Citation: Gao CM, Takezaki T, Wu JZ, Chen MB, Liu YT, Ding JH, Sugimura H, Cao J, Hamajima N, Tajima K. CYP2E1 Rsa I polymorphism impacts on risk of colorectal cancer association with smoking and alcohol drinking. World J Gastroenterol 2007; 13(43): 5725-5730
URL: https://www.wjgnet.com/1007-9327/full/v13/i43/5725.htm
DOI: https://dx.doi.org/10.3748/wjg.v13.i43.5725