Role of bacteria in the etiopathogenesis of inflammatory bowel disease

doi:10.3748/wjg.v13.i42.5571

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Nov 14, 2007 (publication date) through Aug 26, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 14, 2007; 13(42): 5571-5576
Published online Nov 14, 2007. doi: 10.3748/wjg.v13.i42.5571

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Figure 1 Sequential steps of the mechanisms of disease induced by AIEC bacteria: (1) abnormal expression of CEACAM6 in ileal mucosa of CD, inducing (2) AIEC colonization, (3) adhesion and (4) invasion, which allow the bacteria to cross the mucosal barrier. AIEC bacteria can (5) survive and replicate within infected macrophages in the lamina propria, and (6) induce TNF-α secretion.

Citation: Barnich N, Darfeuille-Michaud A. Role of bacteria in the etiopathogenesis of inflammatory bowel disease. World J Gastroenterol 2007; 13(42): 5571-5576
URL: https://www.wjgnet.com/1007-9327/full/v13/i42/5571.htm
DOI: https://dx.doi.org/10.3748/wjg.v13.i42.5571