Copyright
©2007 Baishideng Publishing Group Inc.
World J Gastroenterol. Nov 14, 2007; 13(42): 5581-5593
Published online Nov 14, 2007. doi: 10.3748/wjg.v13.i42.5581
Published online Nov 14, 2007. doi: 10.3748/wjg.v13.i42.5581
Pathogenic factors | |
Categories | Factors (References) |
T cells | Th1[8], CD8+ TCR Vβ14+ T cell[21], CEACAM1[27] |
Cytokines/chemokines | IL-12[8,30], IFN-γ[8,34], IL-18[31,32,139], IL-6[73], IL-16[140], IL-17[38], TNF-α[29,141], MIP-α[142], MIP-3α[143] |
Receptors | CD40[57,58], CD44v7[144], FcεRI[145], GITR[63,64], Complement receptor 3[146] |
Transcription factors | NF-κB p65[65,67,147], RICK[69,70], MAPK p38[70], Smad7[72], Smad3[148] |
Adhesion molecules | Integrinα1β1[80] |
Enzymes | Poly (ADP-ribose) synthetase[149,150], Inducible nitric oxide synthase[151], Angiotensinogen[152], Vanin-1[107] |
Hormones | Leptin[113], Ghrelin[153], Adiponectin[112] |
Others | Geneticfactors[11], Glycolipid[154] |
Regulatory factors | |
Categories | Factors (References) |
T cells | TCRγδ[25,26], NK1.1[20,155,156] |
Cytokines/chemokines | TGF-β[10,44,45], IL-10[44,157,158], IL12 p40[34], IL12 p40-IgG2b[159], IL-2-IgG2b[160], IL-23[39], HGF[48], BFGF[51] |
Receptors | PAR-2[61], TNFR1[56] |
Transcription factors | STAT5b[161], Interferon regulatory factor-1[162], PPARγ[75] |
Enzymes | Indoleamine 2, 3-dioxygenase[163] |
Hormones | Adrenocortical hormones[164,165], NCX-101[166] |
Neurotransmitters | Vasoactive intestinal peptide[167,168], μopioid receptor[169] |
Lipid mediators | Lipoxin A4[170], Marine[171] |
Bacteria and parasite related factors | Yersinia pseudotuberculosis[172], Lactic acid bacteria[173,174], Schistosome eggs[175], Cholera toxin subunit B[176,177] |
Others | Galectin-1[178], Curcumin[179], Catalposide[180], Follistatin[123], Phex gene[181], FTY720[182], Matrine[183] |
- Citation: Kawada M, Arihiro A, Mizoguchi E. Insights from advances in research of chemically induced experimental models of human inflammatory bowel disease. World J Gastroenterol 2007; 13(42): 5581-5593
- URL: https://www.wjgnet.com/1007-9327/full/v13/i42/5581.htm
- DOI: https://dx.doi.org/10.3748/wjg.v13.i42.5581