Chinese medicinal compound delisheng has satisfactory anti-tumor activity, and is associated with up-regulation of endostatin in human hepatocellular carcinoma cell line HepG2 in three-dimensional culture

Figure 7 Sensitivity of HepG2 cells to adriamycin determined by the MTT assay. After the treatment with 0.15625, 0.31250, 0.62500, 1.25000, 2.50000 × 10^-3 g/L adriamycin for 48 h, the cells in-three dimensional cell culture and monolayer culture were cultured with MTT solution and cell inhibition ratio was determined. The cells in monolayer culture were more sensitive to adriamycin (P < 0.01).