Influence of a nucleotide oligomerization domain 1 (NOD1) polymorphism and NOD2 mutant alleles on Crohn's disease phenotype

Table 6 Clinical characteristics of NOD2 WT/WT CD patients according to NOD1 genotype

Clinical features	n1	NOD2 WT/WT
		NOD1:	*1*1	*1*2	*2*2
Age at diagnosis
< 40 yr (A1 + A2)	54		62.962	35.18	1.85
> 40 yr (A3)	13		46.15	46.15	7.69
Location
Ileal (L1)	21		57.14	38.09	4.76
Colonic (L2)	20		70	25	5
Ileocolonic (L3)	26		53.84	46.15	0
Behavior
Non-stricturing,	24		62.5	33.33	4.16
non-penetrating (B1)
Stricturing (B2)	34		61.76	35.29	2.94
Penetrating (B3)	9		44.44	55.55	0
Controls	47		48.93	36.17	14.89

WT: Wildtype. ¹Number of CD patients or controls in each subgroup;

²Values are expressed as the percent of patients in each clinical subgroup.