Influence of a nucleotide oligomerization domain 1 (NOD1) polymorphism and NOD2 mutant alleles on Crohn's disease phenotype

Table 4 Genotype frequencies of ND₁+32656 in CD patients and controls

Group	NOD2	n1	NOD1 genotype, n (%)
			*1*1	*1*2	*2*2
CD		97	58 (59.79)2	36 (37.11)	3 (3.09)
	WT/WT	67	40 (59.70)	25 (37.31)	2 (2.98)
	Mutant3	30	18 (60.00)	11 (36.66)	1 (3.33)
Controls		50	26 (52.00)	17 (34.00)	7 (14.00)
	WT/WT	47	23 (48.93)	17 (36.17)	7 (14.89)
	Mutant	3	3 (100)	0	0

CD: Crohn's disease; WT: Wildtype. ¹Number of CD patients or controls;

²Results are expressed as number of CD patients (% of CD patients);

³NOD2 mutant was considered any subject that inherited at least one copy of the variant allele.