Chinese medicinal compound delisheng has satisfactory anti-tumor activity, and is associated with up-regulation of endostatin in human hepatocellular carcinoma cell line HepG2 in three-dimensional culture

Table 3 Test sensitivity of adriamycin in 3d and 2d cell culture

Concentration (g/L)	Inhibition ratio (%)		P value
	3-d	Monolayer
0.15625 × 10-3	11.40 ± 2.71	10.39 ± 5.07	0.705
0.31250 × 10-3	12.17 ± 6.49	21.31 ± 2.85	0.02
0.62500 ×10-3	18.61 ± 9.41	25.69 ± 8.19	0.24
1.25000 × 10-3	29.45 ± 5.26	41.66 ± 6.52	0.012
2.50000 × 10-3	38.09 ± 20.71	84.56 ± 7.97	0.002

Data were reported as means ± SE (n = 5).