Chinese medicinal compound delisheng has satisfactory anti-tumor activity, and is associated with up-regulation of endostatin in human hepatocellular carcinoma cell line HepG2 in three-dimensional culture

Table 2 Test sensitivity of 5-fluorouracil in 3d and 2d cell culture

Concentration (g/L)	Inhibition ratio (%)		P value
	3-d	Monolayer
6.25 × 10-3	18.25 ± 7.85	33.89 ± 9.41	0.021
12.50 × 10-3	17.51 ± 7.28	39.08 ± 7.74	0.002
25.00 × 10-3	18.18 ± 11.34	43.18 ± 5.92	0.002
50.00 × 10-3	17.87 ± 10.93	67.72 ± 2.18	< 0.001
100.00 × 10-3	36.42 ± 10.54	81.17 ± 2.81	< 0.001