Inhibitory effects of saikosaponin-d on CCl4-induced hepatic fibrogenesis in rats

Figure 1 Light microscopy showing normal liver tissue in control group (A) (HE × 100), degenerated and necrotic liver cells associated with inflammatory cells in model group (B) (HE × 40), attenuated necrosis and infiltration of inflammatory cells after SSd treatment (C) (HE × 40), collagen fibers deposited in spaces of Disse and formation of pseudoloculi in model group (D) (Van Gieson × 40), and liver fibrosis tissue in SSd group (E). The pathological change of liver was much milder in SSd group than in model group (Van Gieson × 40).