Therapeutic effects of Caspase-1 inhibitors on acute lung injury in experimental severe acute pancreatitis

Table 2 Intrapulmonary expression of Caspase-1, IL-1β and IL-18 mRNA in rats with SAP (mean ± SD)

Group	n	Caspase-1 mRNA	IL-1β mRNA	IL-18 mRNA
HC	6	0.57 ± 0.06	0.42 ± 0.03	0.55 ± 0.05
SAP-S
6 h	6	0.71 ± 0.04b	0.75 ± 0.05b	0.82 ± 0.05b
12 h	6	0.71 ± 0.05b	0.81 ± 0.06b	0.83 ± 0.06b
18 h	5	0.72 ± 0.04b	0.79 ± 0.07b	0.82 ± 0.07b
SAP-ICE-I
6 h	6	0.72 ± 0.05b	0.52 ± 0.05bd	0.58 ± 0.06d
12 h	6	0.72 ± 0.06b	0.50 ± 0.04bd	0.55 ± 0.04d
18 h	6	0.69 ± 0.08b	0.49 ± 0.04ad	0.57 ± 0.04d

^aP < 0.05,

^bP < 0.01 vs HC group; ^cP < 0.05,

^dP < 0.01 vs SAP-S group.