Therapeutic effects of Caspase-1 inhibitors on acute lung injury in experimental severe acute pancreatitis

Table 1 Serum IL-1β levels and W/D ratios of the lungs in rats with SAP (mean ± SD)

Group	n	IL-1β (pg/mL)	W/D ratio of lung (g/g)
HC	6	90.13 ± 21.13	4.32 ± 0.33
SAP-S
6 h	6	276.77 ± 44.92b	4.85 ± 0.38a
12 h	6	308.99 ± 34.95b	4.97 ± 0.47b
18 h	5	311.60 ± 46.51b	5.03 ± 0.46b
SAP-ICE-I
6 h	6	151.42 ± 27.26bd	4.38 ± 0.36c
12 h	6	152.47 ± 29.60bd	4.48 ± 0.37c
18 h	6	175.45 ± 29.72bd	4.51 ± 0.36c

^aP < 0.05,

^bP < 0.01 vs HC group;

^cP < 0.05,

^dP < 0.01 vs SAP-S group.