Severe acute pancreatitis: Clinical course and management

Table 6 Early prediction of infected necrosis, infected necrosis + MODS and death using biochemical parameters

	Cut-off	Sensitivity(%)	Specificity(%)	Accuracy(%)
Prediction of infected necrosis
PCT	≥ 1.4 ng/mL	75	68	69a
CRP	≥ 400 mg/L	29	92	76
Prediction of infected necrosis and MODS
PCT	≥ 3.8 ng/mL	80	93	92a
CRP	≥ 410 mg/L	35	93	87
Prediction of death
PCT	≥ 3.8 ng/mL	82	88	88a
Prediction of IN and MODS or death
PCT	≥ 3.8 ng/mL	76	94	92a
CRP	≥ 400 mg/L	35	92	84

PCT: Randomized controlled trial; CRP: C reactive protein; MODS: Multiorgan dysfunction syndrome; IN: Infected necrosis. Receiver operating curve-analysis based on d 3 and 4 onset of symptoms,

^aP < 0.05-0.004, Rau, Annals of Surgery 2007[72].