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©2007 Baishideng Publishing Group Co.
World J Gastroenterol. Oct 7, 2007; 13(37): 5021-5024
Published online Oct 7, 2007. doi: 10.3748/wjg.v13.i37.5021
Published online Oct 7, 2007. doi: 10.3748/wjg.v13.i37.5021
Table 2 Germline mutations of MSH6 gene in 4 probands of HNPCC families
| FamilyNo | Exon | Position ofmutation | Base change | Result | Mutation type |
| H3 | 4.3 | Codon 468 | c.1403G>A | Arg>His | Missense mutation |
| H14 | 6 | Codon 1163 | c.3488A>T | Glu>Val | New SNPs |
| H40 | 4.6 | Codon 666 | c.1996T>C | Ser>Pro | Missense mutation |
| H61 | 9 | Codon 1284 | c.3851C>T | Thr>Met | Missense mutation |
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Citation: Yan SY, Zhou XY, Du X, Zhang TM, Lu YM, Cai SJ, Xu XL, Yu BH, Zhou HH, Shi DR. Three novel missense germline mutations in different exons of
MSH6 gene in Chinese hereditary non-polyposis colorectal cancer families. World J Gastroenterol 2007; 13(37): 5021-5024 - URL: https://www.wjgnet.com/1007-9327/full/v13/i37/5021.htm
- DOI: https://dx.doi.org/10.3748/wjg.v13.i37.5021