Impaired contractility and remodeling of the upper gastrointestinal tract in diabetes mellitus type-1

Figure 4 The distension-induced change in thicknesses of the total esophageal wall structure, the muscle layer, and mucosa-submucosa layer during smooth muscle relaxation with butylscopolamine are illustrated as function of the esophageal radius. The data points represent the multiple measuring points during each distension of the patients and controls. Exponential trend lines (solid lines) of the patients and controls are shown. The total wall thickness and the mucosa-submucosa layer were increased in the diabetic patients.