Interaction of hepatitis C virus with the type I interferon system

doi:10.3748/wjg.v13.i36.4818

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Sep 28, 2007 (publication date) through Nov 5, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 28, 2007; 13(36): 4818-4823
Published online Sep 28, 2007. doi: 10.3748/wjg.v13.i36.4818

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Figure 2 Cellular response to IFNs. Newly synthesized IFN-α/β binds to its cognate receptor (IFNAR) and activates the expression of numerous IFN-stimulated genes (ISGs) via the JAK/STAT pathway. ADAR, P56, OAS and PKR are IFN-stimulated gene products with antiviral properties against HCV. The SOCS and PIAS proteins negatively regulate the IFN-induced signaling pathway at different stages.

Citation: Weber F. Interaction of hepatitis C virus with the type I interferon system. World J Gastroenterol 2007; 13(36): 4818-4823
URL: https://www.wjgnet.com/1007-9327/full/v13/i36/4818.htm
DOI: https://dx.doi.org/10.3748/wjg.v13.i36.4818