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©2007 Baishideng Publishing Group Co.
World J Gastroenterol. Sep 28, 2007; 13(36): 4818-4823
Published online Sep 28, 2007. doi: 10.3748/wjg.v13.i36.4818
Published online Sep 28, 2007. doi: 10.3748/wjg.v13.i36.4818
Figure 2 Cellular response to IFNs.
Newly synthesized IFN-α/β binds to its cognate receptor (IFNAR) and activates the expression of numerous IFN-stimulated genes (ISGs) via the JAK/STAT pathway. ADAR, P56, OAS and PKR are IFN-stimulated gene products with antiviral properties against HCV. The SOCS and PIAS proteins negatively regulate the IFN-induced signaling pathway at different stages.
- Citation: Weber F. Interaction of hepatitis C virus with the type I interferon system. World J Gastroenterol 2007; 13(36): 4818-4823
- URL: https://www.wjgnet.com/1007-9327/full/v13/i36/4818.htm
- DOI: https://dx.doi.org/10.3748/wjg.v13.i36.4818