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©2007 Baishideng Publishing Group Co.
World J Gastroenterol. Sep 14, 2007; 13(34): 4620-4625
Published online Sep 14, 2007. doi: 10.3748/wjg.v13.i34.4620
Published online Sep 14, 2007. doi: 10.3748/wjg.v13.i34.4620
Table 1 Biological function of genes with down-regulated expression
Gene | Chromosomal localization | Biological function | Cy5/Cy3 |
NDP | Xp11.4 | Cross-cell signal transmission, signal transduction, NS development | 4.509 |
SSX4 | Xp11.23 | Transcription regulation, immunoreaction | 4.044 |
CASP1 | 11q23 | Positive regulation of I-kappaB kinase/NF-kappaB cascadereaction, signal transduction, apoptosis | 3.754 |
HPRT1 | Xq26.1 | Cytolysis, lymphocyte proliferation, purine nucleotide synthesis | 3.715 |
TM4SF2 | Xp11.4 | ECM | 3.554 |
DXS1283E | Xp22.3 | Unkown | 3.418 |
DPYS | 8q22 | NS development, signal transduct-ion, nucleotide metabolism | 3.386 |
TYRP1 | 9p23 | Cell metabolism, melanin synthesis | 3.358 |
CADPS | 3p21.1 | Calcium-regulated Exocytosis | 3.238 |
MCF2 | Xq27 | Cytokeleton | 3.187 |
COL4A6 | Xq22 | ECM and ECM synthesis | 3.201 |
F13A1 | 6p25.3-p24.3 | Transcriptional control | 3.108 |
HTR2C | Xq24 | IP3-induced signal pathway | 3.061 |
IL13RA1 | Xq24 | ECM | 3.050 |
OGT | Xq13 | Signal transduction | 3.030 |
TOSO | 1q32.1 | Defence reaction, anti-apoptosis | 2.994 |
MAB21L1 | 13q13 | Positive regulation of cell proliferation, visual development | 2.990 |
CYBB | Xp21.1 | Cross-cell signal transmission, chemotaxis, inflammation, signal transduction | 2.972 |
STK9/CDKL5 | Xp22 | Microduct skeleton and its synthesis, histogenesis | 2.946 |
PTPRG | 3p21-p14 | PTK signal pathway | 2.878 |
ELAVL2 | 9p21 | Transcriptional control | 2.853 |
GLA | Xq22 | Osteoclast differentce regulation,bone resorption, cell adhere | 2.851 |
APXL | Xp22.3 | Channel protein of sodium ion | 2.839 |
SERPINA7 | Xq22.2 | ECM, transport of TH | 2.833 |
- Citation: Li H, Cao HF, Li Y, Zhu ML, Wan J. Changes in gene-expression profiles of colon carcinoma cells induced by wild type K-ras2. World J Gastroenterol 2007; 13(34): 4620-4625
- URL: https://www.wjgnet.com/1007-9327/full/v13/i34/4620.htm
- DOI: https://dx.doi.org/10.3748/wjg.v13.i34.4620