Editorial
Copyright ©2007 Baishideng Publishing Group Co.
World J Gastroenterol. Aug 28, 2007; 13(32): 4295-4305
Published online Aug 28, 2007. doi: 10.3748/wjg.v13.i32.4295
Figure 3
Figure 3 Hepatic fibrosis and hypercarcinogenic state associated with oxidative stress in hepatocytes and HSCs. HSCs are activated by MDA and HNE as well as by ROS. HSCs produce ROS and TGF-β in response to ROS and TGF-β (autocrine) with increased collagen expression in the injured liver.