Apoptotic effect of Epigallocatechin-3-gallate on the human gastric cancer cell line MKN45 via activation of the mitochondrial pathway

Table 1 Apoptotic percentage of MKN45 cells after EGCG insult (mean ± SD, %)

Celldeath	Dose(μmol/L)	Time after treatment
		12 h	18 h	24 h	48 h
Early	Control	0.86 ± 0.19	0.70 ± 0.25	0.91 ± 0.18	0.96 ± 0.12
stage	40	1.04 ± 0.51	2.54 ± 1.79a	1.72 ± 1.30	1.57 ± 0.63
apoptotic	60	1.91 ± 1.30	5.73 ± 0.81a	5.69 ± 2.55a	14.45 ± 3.38a
cells	80	6.30 ± 0.16a	14.93 ± 0.09a	13.05 ± 0.21b	4.09 ± 1.49a
Terminal	Control	0.32 ± 0.25	0.10 ± 0.10	0.30 ± 0.16	0.55 ± 0.05
stage	40	0.65 ± 0.44	0.40 ± 0.26a	0.50 ± 0.17a	5.28 ± 2.29a
apoptotic	60	2.00 ± 0.84	1.06 ± 0.10a	2.49 ± 0.52b	26.45 ± 2.32a
cells	80	3.67 ± 1.36a	8.48 ± 0.14b	19.05 ± 1.06b	62.90 ± 4.70b

^aP < 0.05,

^bP < 0.01 vs control group.