Effect of Qi-protecting powder (Huqi San) on expression of c-jun, c-fos and c-myc in diethylnitrosamine-mediated hepatocarcinogenesis

Table 1 Effect of Huqi San on the number and size of DEN-induced γ-GT positive foci in rat liver (mean ± SD)

Experimental groups	n	Number of γ-GTfoci (per cm2)	Area of γ-GTfoci (mm2/cm2)
Normal group	10	0.23 ± 0.09a	0.18 ± 0.08a
PH group	12	0.31 ± 0.08a	0.21 ± 0.10a
Prevention group	12	4.96 ± 0.72a	5.12 ± 3.62a
Large dose therapeutic group (8 g/kg body weight)	12	7.53 ± 0.88a	8.76 ± 3.97a
Small dose therapeutic group (4 g/kg body weight)	12	12.77 ± 0.93b	13.63 ± 3.44b
Model group	12	29.46 ± 2.17	21.1 ± 2.98

^aP < 0.001,

^bP < 0.01 vs model group; γ-GT: γ-glutamy-transpeptidase.