Antiviral efficacy of adefovir dipivoxil versus lamivudine in patients with chronic hepatitis B sequentially treated with lamivudine and adefovir due to lamivudine resistance

Figure 3 Cumulative rates of sustained hepatitis B e antigen (HBeAg) seroconversion during one year of treatment with lamivudine (dashed line) and after switching to adefovir (continuous line). Only patients with positive HBeAg values at baseline were included in the analysis. Cumulative rates after one-year treatment of lamivudine and adefovir were 13% and 15%, respectively. LMV: lamivudine; ADV: adefovir dipivoxil; HBeAg: hepatitis B e antigen.