Antiviral efficacy of adefovir dipivoxil versus lamivudine in patients with chronic hepatitis B sequentially treated with lamivudine and adefovir due to lamivudine resistance

Figure 2 Mean changes in serum alanine aminotransferase levels after administration of lamivudine (dashed line) and adefovir (continuous line). The levels were obtained at baseline and after 3, 6, 9 and 12 mo of lamivudine and adefovir treatment. The values are not significantly different (P > 0.05). ALT: alanine aminotransferase; LMV: lamivudine; ADV: adefovir dipivoxil.