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©2007 Baishideng Publishing Group Co.
World J Gastroenterol. Aug 7, 2007; 13(29): 3932-3938
Published online Aug 7, 2007. doi: 10.3748/wjg.v13.i29.3932
Published online Aug 7, 2007. doi: 10.3748/wjg.v13.i29.3932
Table 4 Summary for genetic analysis of 55 nonpolypoid colorectal tumors
| Genetic alteration | Frequency | ||
| Mucosal cancer | Submucosal cancer | Total | |
| KLF6, LOH1 (+) | 2/6 (33.3%) | 12/23 (52.2%) | 14/29 (48.3%) |
| KLF6, mutation | 0/6 (0%) | 2/28 (7.1%) | 2/34 (5.9%) |
| p53, LOH (+) | 4/8 (50.0%) | 10/23 (43.5%) | 14/31 (45.2%) |
| p53, overexpression | 2/10 (20.0%) | 17/45 (37.8%) | 19/55 (34.5%) |
| K-ras, mutation | 1/10 (10.0%) | 4/45 (8.9%) | 5/45 (9.1%) |
| B-raf, mutation | 1/10 (10.0%) | 5/45 (11.1%) | 6/55 (10.9%) |
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Citation: Mukai S, Hiyama T, Tanaka S, Yoshihara M, Arihiro K, Chayama K. Involvement of Krüppel-like factor 6 (
KLF6 ) mutation in the development of nonpolypoid colorectal carcinoma. World J Gastroenterol 2007; 13(29): 3932-3938 - URL: https://www.wjgnet.com/1007-9327/full/v13/i29/3932.htm
- DOI: https://dx.doi.org/10.3748/wjg.v13.i29.3932