Immunohistochemical molecular markers as predictors of curability of endoscopically resected submucosal colorectal cancer

doi:10.3748/wjg.v13.i28.3829

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Jul 28, 2007 (publication date) through Nov 24, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Colorectal Cancer

World J Gastroenterol. Jul 28, 2007; 13(28): 3829-3835
Published online Jul 28, 2007. doi: 10.3748/wjg.v13.i28.3829

Table 3 Multivariate analysis of risk factors for LN metastasis of submucosal CRC

Risk factors	P value	Odds ratio
MVD-High	0.0008	16.67
Histologic grade-Unfavorable	0.0116	11.73
Cathepsin D-Positive	0.0071	8.41
LVD-High	0.0027	7.65
Macroscopic type-Superficial	0.0029	7.27
Budding-Positive	0.0160	4.36
MUC1-Positive	0.0266	3.96
Lymphatic involvement Positive	NS	-
Ki-67 LI-High	NS	-
MMP-7-Positive	NS	-

LN: lymph node metastasis; CRC: colorectal cancer: NS: not significant. MVD: microvessel density; LVD: Lymphatic vessel density; MUC1: mucin 1; LI: labeling index; MMP-7: matrix metalloproteinase-7.

Citation: Kaneko I, Tanaka S, Oka S, Yoshida S, Hiyama T, Arihiro K, Shimamoto F, Chayama K. Immunohistochemical molecular markers as predictors of curability of endoscopically resected submucosal colorectal cancer. World J Gastroenterol 2007; 13(28): 3829-3835
URL: https://www.wjgnet.com/1007-9327/full/v13/i28/3829.htm
DOI: https://dx.doi.org/10.3748/wjg.v13.i28.3829