Novel mutations and sequence variants in exons 3-9 of human T Cell Factor-4 gene in sporadic rectal cancer patients stratified by microsatellite instability

Table 1 Sequence analysis of hTCF-4 exons 3-9 in sporadic rectal cancer patients with MSI-H and controls

				Frequency
Exon	Nucleotidechange	Amino acidchange	Mutationtype	Patients(n = 10)	Controls(n = 10)
4	4-position
	continuous
	alteration1	Q131T	Missense	5	0
4	395delC	S132I	Frameshift	4	0
4	450 G > C	Q150H	Missense	1	0
8	868 G > A	V290M	Missense	2	0

¹4-position continuous alteration refers to the mutation (391insA, 392 G > A, 393 A > G and 395delC).