Healing property of the Piper betel phenol, allylpyrocatechol against indomethacin-induced stomach ulceration and mechanism of action

Table 3 The effect of APC and misoprostol on lipid, protein, DNA, SOD and CAT levels of ulcerated gastric tissue of rats¹

Parameters	Group I	Group II2	Group III	Group IV	Group V
MDA (nmol/mg protein)	1.89 ± 0.01	27.04 ± 0.84	24.28 ± 1.12	2.02 ± 0.03	2.62 ± 0.02
Proteins (mg/mL)	16.52 ± 6.05	9.03 ± 1.28	12.55 ± 1.18	14.21 ± 1.8	12.89 ± 0.87
CO (mg/mg protein)	5.26 ± 1.34	17.29 ± 1.83	9.46 ± 2.15	6.03 ± 1.51	6.54 ± 1.12
DNA (mg/g tissue)	1.82 ± 0.22	0.81 ± 0.06	1.12 ± 0.21	3.56 ± 0.05	1.68 ± 0.23
SOD (U/min/mg protein)	22.2 ± 2.34	5.76 ± 2.32	11.58 ± 1.32	21.14 ± 1.24	16.71 ± 2.57
CAT (U/min/mg protein)	21.2 ± 1.12	9.02 ± 2.54	14.20 ± 2.84	19.04 ± 2.15	15.84 ± 2.09

¹Stomach ulceration in rats was induced by oral administration of indomethacin (30 mg/kg body wt.). APC (2 mg/kg body wt.) and misoprostol (1.43 μg/kg body wt.) were used for these experiments. The values are mean ± SE (n = 15).

²The assays were carried out 4 h after indomethacin administration. For other samples these were carried out after 7 d.