Healing property of the Piper betel phenol, allylpyrocatechol against indomethacin-induced stomach ulceration and mechanism of action

Table 2 Comparative healing capacity of APC and misoprostol on ulcerated rats¹

Samples	Ulcer index1	Protection(%)2
Unulcerated control	0 ± 0	-
Ulcerated control (4 h)3	26.71 ± 1.62	0
Ulcerated untreated control	17.64 ± 1.24	36.08 ± 1.38
Ulcerated APC treated	1.78 ± 0.34	93.26 ± 6.77
Ulcerated misoprostol treated	3.91 ± 0.30	85.40 ± 3.51

¹Stomach ulceration in rats was induced by oral administration of indomethacin (30 mg/kg body wt.). APC (2 mg/kg body wt.) and misoprostol (1.43 μg/kg body wt.) were used for these experiments. The ulcer indices values are mean ± SE (n = 15).

²Considering an ulcer index of 100 for the ulcerated, untreated rats. 3The ulcer indices were measured 4 h after indomethacin administration. For other samples the measurement was carried out after 7 d.