Platelet aggregation is affected by nitrosothiols in patients with chronic hepatitis: In vivo and in vitro studies

Table 1 Enrolled subjects: main findings (mean ± SD)

	Controls	HCV-positive CH patients
Total number	50	114
M/F	26/24	59/55
Median age, yr (range)	53 (26-74)	54 (22-81)
ALT (IU/L, nv < 40)	12 ± 11	90.2 ± 60.4
γGT (IU/L, nv < 50)	28 ± 9	77 ± 52
Total proteins (g/dL)	6.8 ± 2.7	7.2 ± 1.2
Albumin (g/dL)	4.1 ± 1.2	3.6 ± 0.8
Total bilirubin (mg/dL)	0.8 ± 0.3	0.9 ± 0.3
Prothrombin time (s)	10.3 ± 2.1	10.5 ± 2.3
Platelets (n x 103/μL)	278 ± 89	159 ± 52
Ishak score for grading (median and range)	-	9 (5-11)
Ishak score for staging	-	3 (2-3)
(median and range)

CH: chronic hepatitis; ALT: alanine aminotransferase; γGT: gamma-glutamyl transpeptidase.