COX-2 expression in gastric cancer and its relationship with angiogenesis using tissue microarray

Table 2 MVD in the gastric cancer and normal mucosa (mean ± SD)

Variable	n	MVD	t/F	P
Tissue character			7.53	0.000
Normal mucosa	38	36.21 ± 18.47
Gastric cancer	92	65.49 ± 20.64
Histologic type			3.68	0.003
Papillary adenocarcinoma	2	39.50 ± 7.78
Well-differentiated adenocarcinoma	9	42.56 ± 20.35
Moderately-differentiated adenocarcinoma	28	56.79 ± 20.97
Poor-differentiated adenocarcinoma	31	72.65 ± 20.49
Mucin adenocarcinom	14	63.64 ± 23.02
Signet-ring cell carcinoma	5	74.40 ± 33.56
Undifferentiated carcinoma	3	44.67 ± 20.23
Histologic type			4.83	0.000
Moderately or well-differentiated	39	54.68 ± 19.78
Poorly or undifferentiated	53	73.88 ± 17.25
Metastasis			4.214	0.043
Negative	26	54.08 ± 24.42
Positive	66	65.08 ± 22.63
Organ metastasis			1.14	0.355
Lymph nodes metastasis	66	65.08 ± 22.63
Liver metastasis	4	82.00 ± 10.61
Ovary metastasis	1	100
Peritoneal metastasis	9	68.44 ± 26.16
Depth of invasion			0.583	0.627
Muscle invasion	4	68.00 ± 19.13
Subserosa invasion	63	60.33 ± 24.28
Serosa exposure invasion	24	65.96 ± 22.68
Borrman type			0.459	0.634
Borrman II	7	55.71 ± 17.17
Borrman III	79	62.92 ± 23.89
Borrman IV	6	61.97 ± 23.55