Reversal of hyperglycemia in diabetic rats by portal vein transplantation of islet-like cells generated from bone marrow mesenchymal stem cells

Figure 6 Islet hormones expression in the pancreas and liver of STZ-induced diabetic rat after D-MSCs transplantation via portal vein. D-MSCs grafts were located in the liver (B, × 400), expressing insulin (INS), glucagons (Gcg), somatostatin (SS) and islet amyloid polypeptide(IAPP); In the remaining pancreatic islets, a few insulin-expressing cells located in the center, rich Gcg-expressing cells setting at the periphery, a few SS-expressing cells and IAPP-expressing cells scattering in the islets (A, × 400).