Phenotypic classification of gastric signet ring cell carcinoma and its relationship with clinicopathologic parameters and prognosis

Figure 3 Clinicopathological features of different intestinal marker expression patterns. V: vascular invasion; LN: lymph node metastasis; W: wall invasion deeper than submucosa layer; D: tumor diameter larger than 5 cm. The number of positive intestinal phenotype markers in one case was positively correlated with higher rates of lymph node metastasis (P < 0.01), vascular invasion (P < 0.01), larger tumor diameter (P < 0.01) and deeper wall invasion (P < 0.05). (Spearman's rank correlation analysis).