Effect of targeted magnetic nanoparticles containing 5-FU on expression of bcl-2, bax and caspase 3 in nude mice with transplanted human liver cancer

Table 1 Comparison of gross tumor volume (mm³, mean ± SD)

Group	n	0	1d	4d	7d	10d	13d
A	8	131.9 ± 4.3	261.0 ± 29.7	362.0 ± 52.9	513.1 ± 67.3	643.9 ± 83.4	776.1 ± 116.2
B	8	133.7 ± 8.3	253.0 ± 27.8	341.5 ± 34.6	473.4 ± 53.2	600.2 ± 72.4	764.7 ± 100.6
Ca	8	134.4 ± 4.7	228.7 ± 26.7	294.8 ± 31.6	364.9 ± 34.5	416.9 ± 64.4	465.0 ± 91.1
Dab	8	135.8 ± 6.8	213.0 ± 18.1	261.5 ± 22.0	315.5 ± 27.6	337.2 ± 32.6	367.8 ± 44.0

^aP < 0.01 vs groups A and B;

^bP < 0.05 vs group C.