Clinical significance of mucosal suppressors of cytokine signaling 3 expression in ulcerative colitis

Figure 2 Relation between the degree of endoscopic (A) and histologic (B) inflammation and levels of SOCS3. The levels of SOCS3 mRNA were determined by quantitative RT-PCR. Box graphic top, bottom, and middle correspond to 75^th, 25^th, and 50^th percentiles (median), respectively. Bar shows 5^th and 95^th percentiles. The mean + SD of endoscopic Matts’ grade was 0.116 + 0.094 for Matts'1, 0.280 + 0.219 for Matts'2, and 0.673 + 0.599 for Matts'3 and 4. The mean + SD of histologic Matts’ grade was 0.038 + 0.048 for Matts’1, 0.124 + 0.102 for Matts'2, 0.250 + 0.174 for Matts'3, 0.597 + 0.371 for Matts'4, and 1.039 + 0.821 for Matts'5. There was a significant correlation between SOCS3 expression in the colonic mucosa and Matts’ grade.