Ultrastructure of oval cells in children with chronic hepatitis B, with special emphasis on the stage of liver fibrosis: The first pediatric study

Figure 4 The distended perisinusoidal space of Disse shows an intermediate hepatocyte-like cell with adhering Kupffer cell (K); the IHC nucleus has less nuclear heterochromatin than the HPC nucleus and contains the nucleolus; the low electron dense cytoplasm with a distinct structure that resembles a peroxysome currently being formed (>) and with granular endoplasmic reticulum profiles. C: a bundle of collagen fibers. A: × 7000; B: × 12 000.