Ultrastructure of oval cells in children with chronic hepatitis B, with special emphasis on the stage of liver fibrosis: The first pediatric study

Figure 3 In a fibrotic field of the periportal space; an intermediate hepatic-like cell and transformed Ito cell. A thick bundle of collagen fibers (C) exerts a pressure on the cell from the outside, causing its focal narrowing; the electron-light cytoplasm contains relatively well developed dark mitochondria and elements of endoplasmic reticulum. Transformed Ito cell (>) adhering to intermediate hepatic-like cell surrounded by collagen deposits (C); H: hepatocyte of the limiting plate of the lobule. A: × 7000; B: × 12 000.