Anti-inflammatory properties of the short-chain fatty acids acetate and propionate: A study with relevance to inflammatory bowel disease

Figure 5 Effects of Short-Chain Fatty Acids on IL-6 release and lactate dehydrogenase (LDH) activity in organ cultures from inflamed mouse colon. Dextran sulphate sodium (DSS) was used to induce colonic inflammation. Organ cultures were exposed to acetate, propionate or butyrate (all 30 mmol/L) for 24 h followed by analysis of IL-6 level (bars) and LDH activity (diamonds) in culture medium. Mean ± SEM (n = 4), ^bP < 0.01.