Advances in small animal mesentery models for in vivo flow cytometry, dynamic microscopy, and drug screening

Figure 14 Effect of a laser pulse (585 nm, 10-ms pulse duration, 0. 5-30 J/cm² radiant exposure) on blood and lymph microvessels in vivo. A: Intact venule (V) and arterioles (A1 and A2) with good blood flow; B: Damage to these microvessels immediately after laser pulse: local hemorrhage (arrow) around the venule (V) and stasis in a small arteriole (A2); C: Intact lymphatic (L) before laser pulse (black dash line shows internal margin of lymphatic wall); D: Laser-induced constriction of the lymphatic, which coincided with stasis in neighboring venules.