Advances in small animal mesentery models for in vivo flow cytometry, dynamic microscopy, and drug screening

Figure 12 High-resolution, high-speed monitoring of cells in blood flow. RBCs are indicated by conventional arrows and triangle; rolling WBCs by arrows originating from filled circles; and direction of flow by dashed lines. A-C: behavior of normal RBCs and WBCs in flow (1250-2500 fps; 40 ×); D: The shapes of normal (left) and diamide-treated (middle) RBCs in single-file flow of small venula (diameter ~10 μm), and (right) adhesion of diamide-treated RBCs to wall of the relatively large venula (diameter -40 μm).