Advances in small animal mesentery models for in vivo flow cytometry, dynamic microscopy, and drug screening

Table 2 Effects of 15-min topical application of different vasoactive drugs on lymph microvessel functions

Drug	Diameter	Phasic activity	Lymph flow velocity
Sodium Nitroprusside (10-5 mol/L)	Dilation	Slight short-time inhibition	Unchanged
N-Nitro-L-Arginine (10-4 mol/L)	Unchanged	Stimulation	Stimulation
Isoprenaline (10-5 mol/L)	Constriction	Inhibition	Inhibition up to stasis
Metoprolol (10-5 mol/L)	Unchanged	Stimulation	Stimulation
Butoxamin (10-5 mol/L)	Unchanged	Slight stimulation	Unchanged
Dymethyl Sulfoxide, (30%)	Constriction	Stimulation	Stimulation in 50% of lymphangions
			Inhibition in 39% of lymphangions (without phasic contractions)