Generation of human/rat xenograft animal model for the study of human donor stem cell behaviors in vivo

Table 3 Percentage of human marker-positive cells detected in PB and BM from MNC-transplanted rats (mean ± SD)

Marker	PB			BM
	3 wk	2 mo	6 mo	2 mo	6 mo
CD45	0.2 ± 0.06	0.15 ± 0.04	0.09 ± 0.01	1.4 ± 0.36	0.1 ± 0.01
	(n = 19)	(n = 17)	(n = 4)	(n = 8)	(n = 4)

Human donation contribution in PB and BM were analyzed by two-color flow cytometry for human-specific marker, i.e. CD45. PB and BM were collected at 3 wk, 2 mo and 6 mo after birth, respectively. Values for human marker-positive cells represent the mean ± SD of human cells found in each of the animals analyzed at a given time point. Other details are as in Figure 1 and Table 2.