Pancreatits after endoscopic retrograde cholangio-pancreatography

Table 1 Studies assessing efficacy of pancreatic stents in prevention of post-ERCP pancreatitis

First author/yr	Study design	Patients	n	Pancreatitis rate without andwith pancreatic stent		P
				Without (%)	With (%)
Smithline 1993[15]	RCT	Pre-cut biliary ES, SOD, small ducts	93	18	14	0.299
Tarnasky 1998[16]	RCT	Biliary ES for SOD	80	26	7	0.03
Elton 1998[17]	Retrospective, case control	Pancreatic ES for all indications	194	12.50	0.70	< 0.003
Fogel 2002[18]	Retrospective, case control	Biliary +/- pancreatic ES for SOD	436	28.20	13.50	< 0.05
Norton 2002[19]	Retrospective, case control	Endosopic ampullectomy	28	11.10	20	> 0.05
Fazel 2003[20]	RCT	Difficult cannulation, biliary ES, SOD	76	28	5	< 0.05
Freeman 2004[21]	Prospective, case control	All attempted major papilla PD stents in high- risk therapeutic ERCP	225	66.70	14.40	0.06
Catalano 2004[22]	Retrospective, case control	Endoscopic ampullectomy	103	16.70	3.30	0.10
Harewood 2005[23]	Prospective, randomized, controlled	Endoscopic ampullectomy	19	33	0	0.02

RCT: randomized controlled trial; ES: endoscopic sphincterotomy; SOD: sphincter of Oddi dysfunction; PD: pancreatic duct.