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©2007 Baishideng Publishing Group Co.
World J Gastroenterol. May 7, 2007; 13(17): 2496-2503
Published online May 7, 2007. doi: 10.3748/wjg.v13.i17.2496
Published online May 7, 2007. doi: 10.3748/wjg.v13.i17.2496
Table 5 QSPkR models from the training set data
| No. | Model | R2 | R | F | S | LOF |
| AUC | ln(AUC) = 2.27895 + 1.22614 (HE7) + 9.96141 (P7) - 20.5953 (V7) + 9.13637 (SA7) | 0.737 | 0.858 | 9.801 | 0.550 | 0.472 |
| t1/2 | ln(t1/2) = 1.49842 + 1.80503 (P7) + 0.492241 (HE7) - 5.26324 (V1) + 3.53476 (P1) | 0.729 | 0.854 | 9.400 | 0.555 | 0.280 |
| Cmax | ln(Cmax) = 2.96161 - 5.92537 (V1) + 2.15698 (MW1) + 0.206369 (P7) + 0.26873 (HE7) | 0.327 | 0.572 | 1.697 | -0.093 | 0.523 |
- Citation: Cheng D, Xu WR, Liu CX. Relationship of quantitative structure and pharmacokinetics in fluoroquinolone antibacterials. World J Gastroenterol 2007; 13(17): 2496-2503
- URL: https://www.wjgnet.com/1007-9327/full/v13/i17/2496.htm
- DOI: https://dx.doi.org/10.3748/wjg.v13.i17.2496