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©2007 Baishideng Publishing Group Co.
World J Gastroenterol. May 7, 2007; 13(17): 2496-2503
Published online May 7, 2007. doi: 10.3748/wjg.v13.i17.2496
Published online May 7, 2007. doi: 10.3748/wjg.v13.i17.2496
Table 3 Descriptors for group R7 of all fluoroquinolones compounds
No. | R7 | ||||||
SA7 | V7 | HE7 | LP7 | RF7 | P7 | MW7 | |
1 | 271.21 | 398.4 | 5.48 | -0.36 | 27.44 | 11.56 | 99.16 |
2 | 299.04 | 445.86 | 5.04 | -0.15 | 31.33 | 13.39 | 113.18 |
3 | 247.54 | 347.95 | 1.46 | -0.72 | 22.15 | 9.72 | 85.13 |
4 | 248.59 | 344.96 | 0.9 | -1 | 21.91 | 9.72 | 85.13 |
5 | 266.41 | 382.26 | 5.33 | -0.36 | 27.44 | 11.56 | 99.16 |
6 | 251.07 | 350.09 | 1.58 | -0.72 | 22.15 | 9.72 | 85.13 |
7 | 265.94 | 383.08 | 3.5 | -0.31 | 26.57 | 11.56 | 99.16 |
8 | 300 | 442.55 | -2.21 | -0.28 | 35.48 | 14.96 | 142.18 |
9 | 261.99 | 381 | 3.58 | -0.31 | 26.57 | 11.56 | 99.16 |
10 | 264.36 | 391.96 | 5.45 | -0.36 | 27.44 | 11.56 | 99.16 |
11 | 260.22 | 378.35 | 3.68 | -0.31 | 26.57 | 11.56 | 99.16 |
12 | 250.06 | 350.92 | 1.37 | -0.72 | 22.15 | 9.72 | 85.13 |
13 | 269.89 | 397.69 | 5.39 | -0.36 | 27.44 | 11.56 | 99.16 |
14 | 258.05 | 374.48 | 5.68 | -0.36 | 27.44 | 11.56 | 99.16 |
15 | 258.5 | 378.79 | 5.73 | -0.36 | 27.44 | 11.56 | 99.16 |
16 | 281.66 | 422.58 | 3 | -0.4 | 28.87 | 12.62 | 111.17 |
17 | 298.38 | 442.76 | 5.55 | 0.11 | 30.99 | 13.39 | 113.18 |
18 | 266.8 | 385.12 | 3.43 | -0.31 | 26.57 | 11.56 | 99.16 |
19 | 244.47 | 346.87 | 4.31 | -1.24 | 24.6 | 10.78 | 97.14 |
20 | 260.91 | 378.28 | 5.31 | -0.36 | 27.44 | 11.56 | 99.16 |
21 | 264 | 387.29 | 5.61 | -0.36 | 27.44 | 11.56 | 99.16 |
22 | 231.53 | 320.13 | 2.75 | -1 | 21.91 | 9.72 | 85.13 |
- Citation: Cheng D, Xu WR, Liu CX. Relationship of quantitative structure and pharmacokinetics in fluoroquinolone antibacterials. World J Gastroenterol 2007; 13(17): 2496-2503
- URL: https://www.wjgnet.com/1007-9327/full/v13/i17/2496.htm
- DOI: https://dx.doi.org/10.3748/wjg.v13.i17.2496