Crohn’s disease, fatigue, and infliximab: Is there a role for cytokines in the pathogenesis of fatigue?

Table 2 Decrease in general fatigue score and CDAI score after infusion mean ± SEM

t/D	General fatigue		CDAI score
	Placebo	Infliximab	Placebo	Infliximab
D 3	3.5 ± 1.1b	2.4 ± 1.5
D 7	3.5 ± 1.1b	3.5 ± 1.6a	40 ± 10.6b	63 ± 18.9b
D 14	1.9 ± 1.1	2.6 ± 1.2a	39 ± 13.3a	65 ± 27.1a
D 21	.	3.6 ± 1.4a		72 ± 28.9a
D 28	.	3.8 ± 1.4a		68 ± 36.2

^aP≤ 0.05,

^bP≤ 0.01 vs baseline. CDAI: Crohn’s disease activity index.