Lactobacillus plantarum inhibits epithelial barrier dysfunction and interleukin-8 secretion induced by tumor necrosis factor-α

Figure 3 Effect of L. plantarum on the ERK pathway. Caco-2 cells were incubated with L. plantarum, TNF-α or L. plantarum plus TNF-α. Cell lysates were immunoblotted with antibodies against phosphorylated ERK and total ERK. L. plantarum inhibited TNF-α-induced activation of ERK-1 and -2. LP: L. plantarum; TNF, TNF-α.