Significance of hepatitis B virus surface antigen, hepatitis C virus expression in hepatocellular carcinoma and pericarcinomatous tissues

Table 2 Correlation between AFP and expressions of HBsAg and HCV in HCC and noncancerous tissues

Groups	n	AFP negative	AFP positive	Positive rates of AFP(%)	Mean of AFP(ng/mL)	Average sum of ranks
NBNC	6	4	2	33.3	53.3	14.3
HBsAg	66	22	44	66.7	352.6	48.7
HCV	7	3	4	57.1	348.2	50.1
BC	21	3	18	85.7	541.2	66.7

AFP negative means AFP value ≤ 20 ng/mL and AFP positive means AFP value ≥ 20 ng/ mL. Rank-sum test, H = 16.11, P = 0.001; coparation between two groups, P < 0.001. Spearman correlation analysis, r_s = 0.38, t = 4.06, P = 0.0001. chi square test, Fisher probabilities P = 0.0415.