Clinical heterogeneity in autoimmune acute liver failure

Table 2 Clinical features at d 1 of survivors and non-survivors

Variables	In-hospital survival (n = 6) median (range)	In-hospital non-survival (n = 5) median (range)	P
Age (yr)	52 (17-67)	29.5 (18–66)	0.43
HE grade (III or IV), n (%)	1 (16)	4 (80)	0.10
Body mass index (m/kg2)	26.9 (22–31.1)	25.1 (20–35)	0.39
APACHE score	8 (6–13)	20 (11–23)	0.08
Total bilirubin (mg/dL)	15.3 (7.6–21.9)	22.3 (8.4–26.8)	0.35
Alanine aminotransferase (IU/L)	358 (217–683)	127 (23–541)	0.35
INR	1.7 (1.5–8.12)	2.05 (1.5–3.6)	0.35
Creatinine (mg/dL)	0.9 (0.6–2.3)	1.25 (0.9–6.6)	0.20
Serum sodium (mEq/L)	134 (131–138)	134 (125–149)	0.35
SIRS (yes), n (%)	0	1 (20)	0.45
Sepsis (yes), n (%)	1 (16)	2 (33.2)	0.42
Severe sepsis (yes), n (%)	1 (16)	3 (60)	0.19
Septic shock (yes), n (%)	0	0	NS
Multiple organic failure (yes), n (%)	0	5 (100)	0.02
Corticosteroids (yes), n (%)	5 (83)	1 (20)	0.06

HE: hepatic encephalopathy grade; APACHE: acute physiology and chronic health evaluation; SIRS: systemic inflammatory response syndrome.