Clinical heterogeneity in autoimmune acute liver failure

Table 1 Clinical features at time of diagnosis

Case No.	Age(yr)	IAHSS	New onset AIH	BMI(m/kg2)	HE	SIRS	Bilirubin(mg/dL)	ALT(IU/L)	ALP(UI/L)	INR	Globulin(g/dL)	Creatinine(mg/dL)	ANA	Corticosteroids
1.31	65	17	Yes	31.1	2	Yes	21.9	309	274	1.60	4.1	1.1	1:40	Yes
1.22	17	17	Yes	22.0	3	Yes	15.3	358	136	1.50	2.5	0.9	1:40	Yes
23	66	17	No	20.0	2	Yes	8.4	31	207	1.50	4.4	0.9	1:80	Yes
1.24	28	17	Yes	30.3	2	Yes	22.9	128	262	1.90	5.7	1.1	1:80	Yes
1.25	52	14	Yes	27.5	2	No	21.2	217	186	1.90	4.5	0.6	1:40	No
16	17	20	Yes	22.5	2	No	7.6	414	271	1.70	7.7	0.8	1:80	Yes
7	31	18	No	19.9	4	Yes	22.0	541	138	3.60	2.9	6.6	1:80	Yes
8	25	14	No	35.0	3	Yes	26.8	23	309	1.90	3.1	2.7	1:40	No
1.39	67	13	Yes	26.9	2	No	13.8	683	135	8.12	2.4	2.3	1:80	No
10	18	12	Yes	27.0	3	Yes	22.6	126	120	2.20	2.7	1.1	1:40	No
11	33	13	Yes	23.3	3	Yes	20.1	173	199	3.60	4.3	1.4	1:80	No

IAHSS: international autoimmune hepatitis scoring system; HE: hepatic encephalopathy grade; SIRS: systemic inflammatory response syndrome; ALT: alanine aminotransferase; ALP: alkaline phosphatase; INR: international normalized ratio; ANA: antinuclear antibody; BMI: body mass index.

¹Cases treated with corticosteroids,

²Cases that survived one month, ³Cases that survived more than three years.