A comparative review of HLA associations with hepatitis B and C viral infections across global populations

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Mar 28, 2007 (publication date) through Jul 28, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 28, 2007; 13(12): 1770-1787
Published online Mar 28, 2007. doi: 10.3748/wjg.v13.i12.1770

Table 9 HLA association with response to interferon therapy in chronic hepatitis (B and C) patients across global population

HLA	Effect	Country	R	NR	References
Hepatitis B
HLA DQA10501 and DQB10301	Responsiveness	China	32	28	[85]
HLA-DRB1*14	Responsiveness	China	11	24	[14]
HLA DRB104,DQA10303	Non-responsiveness	China	32	28	[85]
HLA-DRB1*07 (HBV type c)	Non-responsiveness	China	7		[152]
HLA-DQB1*07	Low response	China	11	24	[14]
Hepatitis C
Non responsiveness
HLAIHLA B54	Non responsiveness	Japan	20	47	[86]
HLAII, HLA DR9	Non responsiveness	Japan			[153]
HLA DR6	Non responsiveness	Japan	21	32	[154]
HLA DRB1*04 (males and HCV1b)	Non responsiveness	China	10	11	[84]
HLA B1*13	Non responsiveness	Turkey			[155]
DRB1*07	Non responsiveness	France	50	120	[75]
Responsiveness
HLAIHLA B55, B62 and Cw3	Responsiveness	Japan	54	118	[156]
HLA B51, CW1	Responsiveness	Japan			[153]
HLA B44	Responsiveness to Interfron + Ribavirin	Spain	53	52	[87]
HLAII HLA DRB*10101	Responsiveness	Japan	32	106	[157]
HLA DR6	Responsiveness	Japan	21	32	[154]
HLA DRB1*07 (females and HCV 2b)	Responsiveness	China	10	11	[84]
HLA DR2	Responsiveness	Egypt	25	30	[158]
DQB1*06(HCV genotype 1)	Responsiveness	France	50	120	[75]
HLA DRB1*0404	Responsiveness	Canada	6	64	[88]
Haplotypes
HLA A-24-B54-DR4	Non responsiveness	Japan	20	47	[86]
HLA B7-DRB10101	Responsiveness	Japan	32	106	[157]
DRB10701-DQA10201-DQB1*02	Responsiveness	Poland	29	26	[108]

Citation: Singh R, Kaul R, Kaul A, Khan K. A comparative review of HLA associations with hepatitis B and C viral infections across global populations. World J Gastroenterol 2007; 13(12): 1770-1787
URL: https://www.wjgnet.com/1007-9327/full/v13/i12/1770.htm
DOI: https://dx.doi.org/10.3748/wjg.v13.i12.1770