Mechanism of apoptotic effects induced selectively by ursodeoxycholic acid on human hepatoma cell lines

Figure 5 A: Effects of UDCA on production of cyclins and Cdks in HepG2 and BEL7402 cells treated with various concentrations of UDCA (0. 1, 0.2, 0.4, 0.8, 1.0 mmol/L) for 48 h; B: Effects of UDCA treatment on protein levels of p21^WAF1/CIP1, p53, p^Rb in HepG2 and BEL7402. The cells were treated with 0.8 mmol/L UDCA for 48 h.