Mechanism of apoptotic effects induced selectively by ursodeoxycholic acid on human hepatoma cell lines

Figure 2 Induction of internucleosomal DNA fragmentation by UDCA. Cells were incubated without or with various concentrations of UDCA (0.4 mmol/L, 0.8 mmol/L, 1.0 mmol/L) for 48 h. DNA was extracted and analyzed by 1.5% agarose gel electrophoresis in the presence of ethidium bromide staining.